Characteristics of the Adeno-Associated Virus Preintegration Site in Human Chromosome 19: Open Chromatin Conformation and Transcription-Competent Environment

Adeno-associated virus (AAV) establishes latency in infected cells by integrating into the cellular genome, with a high preference for a unique region, called AAVS1, of the human chromosome 19. The AAV proteins Rep78 and -68 are postulated to initiate the site-specific integration process by binding...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lamartina, Stefania, Sporeno, Elisabetta, Fattori, Elena, Toniatti, Carlo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112291/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10906224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.16.7671-7677.2000
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