Simian Immunodeficiency Virus (SIV) gag DNA-Vaccinated Rhesus Monkeys Develop Secondary Cytotoxic T-Lymphocyte Responses and Control Viral Replication after Pathogenic SIV Infection

The potential contribution of a plasmid DNA construct to vaccine-elicited protective immunity was explored in the simian immunodeficiency virus (SIV)/macaque model of AIDS. Making use of soluble major histocompatibility class I/peptide tetramers and peptide-specific killing assays to monitor CD8(+)...

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Bibliographische Detailangaben
Hauptverfasser: Egan, Michael A., Charini, William A., Kuroda, Marcelo J., Schmitz, Jörn E., Racz, Paul, Tenner-Racz, Klara, Manson, Kelledy, Wyand, Michael, Lifton, Michelle A., Nickerson, Christie E., Fu, Tongming, Shiver, John W., Letvin, Norman L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112269/
https://ncbi.nlm.nih.gov/pubmed/10906202
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