Evolution of Circulating Wild Poliovirus and of Vaccine-Derived Poliovirus in an Immunodeficient Patient: a Unifying Model

We determined nucleotide sequences of the VP1 and 2AB genes and portions of the 2C and 3D genes of two evolving poliovirus lineages: circulating wild viruses of T geotype and Sabin vaccine-derived isolates from an immunodeficient patient. Different regions of the viral RNA were found to evolve nonsy...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Gavrilin, Gene V., Cherkasova, Elena A., Lipskaya, Galina Y., Kew, Olen M., Agol, Vadim I.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2000
Subjects:	Recombination and Evolution
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10906191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.16.7381-7390.2000
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