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Two Putative α-Helical Domains of Human Immunodeficiency Virus Type 1 Vpr Mediate Nuclear Localization by at Least Two Mechanisms

To identify the domains of Vpr that are involved nuclear localization, we transfected HeLa cells with a panel of expression vectors that encode mutant Vpr protein with deletions or substitutions within putative domains. Immunofluorescence staining of transfected cells revealed that wild-type Vpr was...

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Bibliographic Details
Published in:J Virol
Main Authors: Kamata, Masakazu, Aida, Yoko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.7179-7186.2000
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