The Chicken Anemia Virus-Derived Protein Apoptin Requires Activation of Caspases for Induction of Apoptosis in Human Tumor Cells

The chicken anemia virus protein Apoptin has been shown to induce apoptosis in a large number of transformed and tumor cell lines, but not in primary cells. Whereas many other apoptotic stimuli (e.g., many chemotherapeutic agents and radiation) require functional p53 and are inhibited by Bcl-2, Apop...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Danen-van Oorschot, A. A. A. M., van der Eb, A. J., Noteborn, M. H. M.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Virus-Cell Interactions
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.7072-7078.2000
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