Rescue of Very Virulent and Mosaic Infectious Bursal Disease Virus from Cloned cDNA: VP2 Is Not the Sole Determinant of the Very Virulent Phenotype

Many recent outbreaks of infectious bursal disease in commercial chicken flocks worldwide are due to the spread of very virulent strains of infectious bursal disease virus (vvIBDV). The molecular determinants for the enhanced virulence of vvIBDV compared to classical IBDV are unknown. The lack of a...

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Bibliographic Details
Main Authors: Boot, Hein J., ter Huurne, A. Agnes H. M., Hoekman, Arjan J. W., Peeters, Ben P. H., Gielkens, Arno L. J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112185/
https://ncbi.nlm.nih.gov/pubmed/10888607
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