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The bfl-1 Gene Is Transcriptionally Upregulated by the Epstein-Barr Virus LMP1, and Its Expression Promotes the Survival of a Burkitt's Lymphoma Cell Line

The recently identified bfl-1 gene (also known as A1 or GRS), a homologue of bcl-2, encodes an antiapoptotic protein that suppresses apoptosis induced by the p53 tumor suppressor protein and exhibits proliferative and potent cooperative transforming activities. We show that elevated levels of bfl-1...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: D'Souza, Brendan, Rowe, Martin, Walls, Dermot
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112177/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6652-6658.2000
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