Mutations in the E1 Hydrophobic Domain of Rubella Virus Impair Virus Infectivity but Not Virus Assembly

Rubella virus (RV) virions contain three structural proteins, a capsid protein that interacts with viral genomic RNA to form a nucleocapsid and two membrane glycoproteins, E2 and E1. We found that substitution of either an aspartic acid residue at Gly93 (G93D) or a glycine residue at Pro104 (P104G)...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Qiu, Zhiyong, Yao, Jiansheng, Cao, Hanwei, Gillam, Shirley
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6637-6642.2000
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