Interdependence of Hemagglutinin Glycosylation and Neuraminidase as Regulators of Influenza Virus Growth: a Study by Reverse Genetics

The hemagglutinin (HA) of fowl plague virus A/FPV/Rostock/34 (H7N1) carries two N-linked oligosaccharides attached to Asn123 and Asn149 in close vicinity to the receptor-binding pocket. In previous studies in which HA mutants lacking either one (mutants G1 and G2) or both (mutant G1,2) glycosylation...

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Pubblicato in:	J Virol
Autori principali:	Wagner, Ralf, Wolff, Thorsten, Herwig, Astrid, Pleschka, Stephan, Klenk, Hans-Dieter
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6316-6323.2000
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