Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50/Rta Protein Activates the Entire Viral Lytic Cycle in the HH-B2 Primary Effusion Lymphoma Cell Line

Rta, the gene product of Kaposi's sarcoma-associated herpesvirus (KSHV) encoded mainly in open reading frame 50 (ORF50), is capable of activating expression of viral lytic cycle genes. What was not demonstrated in previous studies was whether KSHV Rta was competent to initiate the entire viral...

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Bibliographische Detailangaben
Hauptverfasser: Gradoville, Lyndle, Gerlach, Jennifer, Grogan, Elizabeth, Shedd, Duane, Nikiforow, Sarah, Metroka, Craig, Miller, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112123/
https://ncbi.nlm.nih.gov/pubmed/10846108
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