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The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells

Human immunodeficiency virus type 2 (HIV-2), like other lentiviruses, is capable of infecting nondividing T cells and macrophages. The present work shows that in HIV-2-infected cells, Vpx is necessary for efficient nuclear import of the preintegration complex. In agreement with this finding, the sub...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Pancio, Heather A., Vander Heyden, Nancy, Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112115/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.6162-6167.2000
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