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Depletion of Lymphocytes and Diminished Cytokine Production in Mice Infected with a Highly Virulent Influenza A (H5N1) Virus Isolated from Humans

Previously, we observed that several virulent influenza A (H5N1) viruses which caused severe or fatal disease in humans were also lethal in BALB/c mice following dissemination of the virus to solid organs, including the brain. In contrast, one particular human H5N1 virus was nonlethal in mice and sh...

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Detalhes bibliográficos
Main Authors: Tumpey, Terrence M., Lu, Xiuhua, Morken, Timothy, Zaki, Sherif R., Katz, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112109/
https://ncbi.nlm.nih.gov/pubmed/10846094
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