The Intracytoplasmic Domain of the Env Transmembrane Protein Is a Locus for Attenuation of Simian Immunodeficiency Virus SIVmac in Rhesus Macaques

The human and simian immunodeficiency virus (HIV-1 and SIVmac) transmembrane proteins contain unusually long intracytoplasmic domains (ICD-TM). These domains are suggested to play a role in envelope fusogenicity, interaction with the viral matrix protein during assembly, viral infectivity, binding o...

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Autores principales: Shacklett, Barbara L., Weber, Claudia Jo, Shaw, Karen E. S., Keddie, Elise M., Gardner, Murray B., Sonigo, Pierre, Luciw, Paul A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC112078/
https://ncbi.nlm.nih.gov/pubmed/10846063
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