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The E4-6/7 Protein Functionally Compensates for the Loss of E1A Expression in Adenovirus Infection

The E1A gene products are required and sufficient for activation of adenovirus gene expression in cultured cells. The E4-6/7 gene product induces the binding of the cellular transcription factor E2F to the viral E2a promoter region. The induction of E2F binding to the E2a promoter in vitro is direct...

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Detalhes bibliográficos
Main Authors: O'Connor, Robert J., Hearing, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112076/
https://ncbi.nlm.nih.gov/pubmed/10846061
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