Recombinant Chimeric Yellow Fever-Dengue Type 2 Virus Is Immunogenic and Protective in Nonhuman Primates

A chimeric yellow fever (YF)-dengue type 2 (dengue-2) virus (ChimeriVax-D2) was constructed using a recombinant cDNA infectious clone of a YF vaccine strain (YF 17D) as a backbone into which we inserted the premembrane (prM) and envelope (E) genes of dengue-2 virus (strain PUO-218 from a case of den...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Guirakhoo, F., Weltzin, R., Chambers, T. J., Zhang, Z.-X., Soike, K., Ratterree, M., Arroyo, J., Georgakopoulos, K., Catalan, J., Monath, T. P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.12.5477-5485.2000
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