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Retroviral Vector Targeting to Human Immunodeficiency Virus Type 1-Infected Cells by Receptor Pseudotyping

We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduct...

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Détails bibliographiques
Auteurs principaux: Somia, Nikunj V., Miyoshi, Hiroyuki, Schmitt, Mark J., Verma, Inder M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC111959/
https://ncbi.nlm.nih.gov/pubmed/10756057
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