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Establishment of Monoclonal Anti-Retroviral gp70 Autoantibodies from MRL/lpr Lupus Mice and Induction of Glomerular gp70 Deposition and Pathology by Transfer into Non-Autoimmune Mice

Several strains of mice, including MRL/MpJ mice homozygous for the Fas mutant lpr gene (MRL/lpr mice), F(1) hybrids of New Zealand Black and New Zealand White mice, and BXSB/MpJ mice carrying a Y-linked autoimmune acceleration gene, spontaneously develop immune complex-mediated glomerulonephritis. T...

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Detalhes bibliográficos
Main Authors: Tabata, Nobutada, Miyazawa, Masaaki, Fujisawa, Ryuichi, Takei, Yumiko A., Abe, Hiroyuki, Hashimoto, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111926/
https://ncbi.nlm.nih.gov/pubmed/10756024
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