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Mutation Analysis of the GDD Sequence Motif of a Calicivirus RNA-Dependent RNA Polymerase

The RNA-dependent RNA polymerase from rabbit hemorrhagic disease virus, a calicivirus, is known to have a conserved GDD amino acid motif and several additional regions of sequence homology with all types of polymerases. To test whether both aspartic acid residues are in fact involved in the catalyti...

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Main Authors: Vázquez, Ana López, Alonso, José M. Martín, Parra, Francisco
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2000
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC111898/
https://ncbi.nlm.nih.gov/pubmed/10729164
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