A Murine Leukemia Virus (MuLV) Long Terminal Repeat Derived from Rhesus Macaques in the Context of a Lentivirus Vector and MuLV gag Sequence Results in High-Level Gene Expression in Human T Lymphocytes

We constructed human immunodeficiency virus type 1 (HIV-1) vectors that will allow higher levels of gene expression in T cells. Gene expression under the control of an internal cytomegalovirus (CMV) immediate-early promoter in a self-inactivating lentiviral vector (CSCG) is 4- to 15-fold lower in T-...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kung, Sam K. P., An, Dong Sung, Chen, Irvin S. Y.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111877/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10729143/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.8.3668-3681.2000
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