Asymmetric Subunit Organization of Heterodimeric Rous Sarcoma Virus Reverse Transcriptase αβ: Localization of the Polymerase and RNase H Active Sites in the α Subunit

The genes encoding the α (63-kDa) and β (95-kDa) subunits of Rous sarcoma virus (RSV) reverse transcriptase (RT) or the entire Pol polypeptide (99 kDa) were mutated in the conserved aspartic acid residue Asp 181 of the polymerase active site (YMDD) or in the conserved Asp 505 residue of the RNase H...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Werner, Susanne, Wöhrl, Birgitta M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3245-3252.2000
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