Mutational Analysis of Adeno-Associated Virus Type 2 Rep68 Protein Endonuclease Activity on Partially Single-Stranded Substrates

The endonuclease activity of the Rep68 and Rep78 proteins (Rep68/78) of adeno-associated virus type 2 (AAV) cuts at the terminal resolution site (trs) within the hairpin structure formed by the AAV inverted terminal repeats. Recent studies suggest that a DNA unwinding function of Rep68/78 may be req...

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Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Davis, Michael D., Wu, Jianwen, Owens, Roland A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2000
Θέματα:	Replication
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10684315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.6.2936-2942.2000
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