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Nuclear Matrix Attachment Regions of Human Papillomavirus Type 16 Repress or Activate the E6 Promoter, Depending on the Physical State of the Viral DNA

Two nuclear matrix attachment regions (MARs) bracket a 550-bp segment of the long control region (LCR) containing the epithelial cell-specific enhancer and the E6 promoter of human papillomavirus type 16 (HPV-16). One of these MARs is located in the 5′ third of the LCR (5′-LCR-MAR); the other lies w...

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Main Authors: Stünkel, Walter, Huang, Zhonghui, Tan, Shyh-Han, O'Connor, Mark J., Bernard, Hans-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC111737/
https://ncbi.nlm.nih.gov/pubmed/10684263
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