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Clustered Charge-to-Alanine Mutagenesis of the Vaccinia Virus H5 Gene: Isolation of a Dominant, Temperature-Sensitive Mutant with a Profound Defect in Morphogenesis

The vaccinia virus H5 gene encodes a 22.3-kDa phosphoprotein that is expressed during both the early and late phases of viral gene expression. It is a major component of virosomes and has been implicated in viral transcription and, as a substrate of the B1 kinase, may participate in genome replicati...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: DeMasi, Joseph, Traktman, Paula
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666270/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2393-2405.2000
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