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Induction of the Cellular E2F-1 Promoter by the Adenovirus E4-6/7 Protein

The adenovirus type 5 (Ad5) E4-6/7 protein interacts directly with different members of the E2F family and mediates the cooperative and stable binding of E2F to a unique pair of binding sites in the Ad5 E2a promoter region. This induction of E2F DNA binding activity strongly correlates with increase...

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Autors principals: Schaley, Joel, O'Connor, Robert J., Taylor, Laura J., Bar-Sagi, Dafna, Hearing, Patrick
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC111689/
https://ncbi.nlm.nih.gov/pubmed/10666238
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