Hepatitis C Virus-Encoded Enzymatic Activities and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In Vivo

Hepatitis C virus (HCV) infection is a widespread major human health concern. Significant obstacles in the study of this virus include the absence of a reliable tissue culture system and a small-animal model. Recently, we constructed full-length HCV cDNA clones and successfully initiated HCV infecti...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kolykhalov, Alexander A., Mihalik, Kathy, Feinstone, Stephen M., Rice, Charles M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.2046-2051.2000
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