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Replication of Herpes Simplex Virus Type 1 within Trigeminal Ganglia Is Required for High Frequency but Not High Viral Genome Copy Number Latency

The replication properties of a thymidine kinase-negative (TK(−)) mutant of herpes simplex virus type 1 (HSV-1) were exploited to examine the relative contributions of replication at the body surface and within trigeminal ganglia (TG) on the establishment of latent infections. The replication of a T...

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Библиографические подробности
Главные авторы: Thompson, Richard L., Sawtell, N. M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC111617/
https://ncbi.nlm.nih.gov/pubmed/10623759
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