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Second-Site Changes Affect Viability of Amphotropic/Ecotropic Chimeric Enveloped Murine Leukemia Viruses

Chimeras were previously generated between the ecotropic (Moloney-MuLV) and amphotropic (4070A) SU and TM proteins of murine leukemia virus (MuLV). After passage in D17 cells, three chimeras with junctions in the C terminus of SU (AE5, AE6, and AE7), showed improved kinetics of viral spreading, sugg...

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Pubblicato in:J Virol
Autori principali: O'Reilly, Lucille, Roth, Monica J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.899-913.2000
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