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The Nuclear Export Signal within the E4orf6 Protein of Adenovirus Type 5 Supports Virus Replication and Cytoplasmic Accumulation of Viral mRNA

During the late phase of adenovirus infection, viral mRNA is efficiently transported from the nucleus to the cytoplasm while most cellular mRNA species are retained in the nucleus. Two viral proteins, E1B-55 kDa and E4orf6, are both necessary for these effects. The E4orf6 protein of adenovirus type...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Weigel, Silke, Dobbelstein, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111596/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.764-772.2000
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