Glial Cell-Specific Regulation of the JC Virus Early Promoter by Large T Antigen

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease that results from an oligodendrocyte infection caused by JC virus. The JC virus early promoter directs cell-specific expression of the viral replication factor large T antigen, and thus transcriptional regulation const...

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Bibliographic Details
Main Authors: Kim, Hee-Sun, Goncalves, Nuno M., Henson, John W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC111595/
https://ncbi.nlm.nih.gov/pubmed/10623737
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