Large-Plaque Mutants of Sindbis Virus Show Reduced Binding to Heparan Sulfate, Heightened Viremia, and Slower Clearance from the Circulation
Laboratory strains of Sindbis virus must bind to the negatively charged glycosaminoglycan heparan sulfate in order to efficiently infect cultured cells. During infection of mice, however, we have frequently observed the development of large-plaque viral mutants with a reduced ability to bind to hepa...
Na minha lista:
| 發表在: | J Virol |
|---|---|
| Principais autores: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2000
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111583/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.644-651.2000 |
| 標簽: |
沒有標簽, 成為第一個標記此記錄!
|