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cis Expression of the F12 Human Immunodeficiency Virus (HIV) Nef Allele Transforms the Highly Productive NL4-3 HIV Type 1 to a Replication-Defective Strain: Involvement of both Env gp41 and CD4 Intracytoplasmic Tails

F12 human immunodeficiency virus type 1 (HIV-1) nef is a naturally occurring nef mutant cloned from the provirus of a nonproductive, nondefective, and interfering HIV-1 variant (F12-HIV). We have already shown that cells stably transfected with a vector expressing the F12-HIV nef allele do not downr...

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Detalhes bibliográficos
Main Authors: Olivetta, Eleonora, Pugliese, Katherina, Bona, Roberta, D'Aloja, Paola, Ferrantelli, Flavia, Santarcangelo, Anna Claudia, Mattia, Gianfranco, Verani, Paola, Federico, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111560/
https://ncbi.nlm.nih.gov/pubmed/10590138
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