Conditional Site-Specific Integration into Human Chromosome 19 by Using a Ligand-Dependent Chimeric Adeno-Associated Virus/Rep Protein

It is of great interest for gene therapy to develop vectors that drive the insertion of a therapeutic gene into a chosen specific site on the cellular genome. Adeno-associated virus (AAV) is unique among mammalian viruses in that it integrates into a distinct region of human chromosome 19 (integrati...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Rinaudo, Daniela, Lamartina, Stefania, Roscilli, Giuseppe, Ciliberto, Gennaro, Toniatti, Carlo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10590116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.1.281-294.2000
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