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Integrins α2β1 and α4β1 Can Mediate SA11 Rotavirus Attachment and Entry into Cells

Most mammalian rotaviruses contain tripeptide amino acid sequences in outer capsid proteins VP4 and VP7 which have been shown to act as ligands for integrins α2β1 and α4β1. Peptides containing these sequences and monoclonal antibodies directed to these integrins block rotavirus infection of cells. H...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Hewish, Marilyn J., Takada, Yoshikazu, Coulson, Barbara S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10590110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.1.228-236.2000
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