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Differential Glycosylation of the Cas-Br-E Env Protein Is Associated with Retrovirus-Induced Spongiform Neurodegeneration

The wild mouse ecotropic retrovirus, Cas-Br-E, induces progressive, noninflammatory spongiform neurodegenerative disease in susceptible mice. Functional genetic analysis of the Cas-Br-E genome indicates that neurovirulence maps to the env gene, which encodes the surface glycoprotein responsible for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lynch, William P., Sharpe, Arlene H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111494/
https://ncbi.nlm.nih.gov/pubmed/10627570
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