A Central Role for CD4(+) T Cells and RANTES in Virus-Induced Central Nervous System Inflammation and Demyelination

Infection of C57BL/6 mice with mouse hepatitis virus (MHV) results in a demyelinating encephalomyelitis characterized by mononuclear cell infiltration and white matter destruction similar to the pathology of the human demyelinating disease multiple sclerosis. The contributions of CD4(+) and CD8(+) T...

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Main Authors: Lane, Thomas E., Liu, Michael T., Chen, Benjamin P., Asensio, Valérie C., Samawi, Roger M., Paoletti, Alyssa D., Campbell, Iain L., Kunkel, Stephen L., Fox, Howard S., Buchmeier, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111476/
https://ncbi.nlm.nih.gov/pubmed/10627552
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