Orf Virus Encodes a Novel Secreted Protein Inhibitor of Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-2

The parapoxvirus orf virus encodes a novel soluble protein inhibitor of ovine granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-2 (IL-2). The GM-CSF- and IL-2-inhibitory factor (GIF) gene was expressed as an intermediate-late viral gene in orf virus-infected cells. GIF formed...

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Pubblicato in:	J Virol
Autori principali:	Deane, David, McInnes, Colin J., Percival, Ann, Wood, Ann, Thomson, Jackie, Lear, Andrea, Gilray, Janice, Fleming, Stephen, Mercer, Andrew, Haig, David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10627542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.3.1313-1320.2000
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