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Toward a More Accurate Quantitation of the Activity of Recombinant Retroviruses: Alternatives to Titer and Multiplicity of Infection

In this paper, we present a mathematical model with experimental support of how several key parameters govern the adsorption of active retrovirus particles onto the surface of adherent cells. These parameters, including time of adsorption, volume of virus, and the number, size, and type of target ce...

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Main Authors: Andreadis, Stylianos, Lavery, Thomas, Davis, Howard E., Le Doux, Joseph M., Yarmush, Martin L., Morgan, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC111460/
https://ncbi.nlm.nih.gov/pubmed/10627536
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