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Expression of a Constitutively Active Cdc42 Homologue Promotes Development of Sclerotic Bodies but Represses Hyphal Growth in the Zoopathogenic Fungus Wangiella (Exophiala) dermatitidis

In contrast to the CDC42 homologues of Saccharomyces cerevisiae and Schizosaccharomyces pombe, the WdCDC42 gene in the human pathogenic fungus Wangiella (Exophiala) dermatitidis was found to be nonessential for cell viability. Expression of the constitutively active allele wdcdc42(G14V) at 37°C indu...

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Autors principals: Ye, Xiangcang, Szaniszlo, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC111375/
https://ncbi.nlm.nih.gov/pubmed/10940039
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