Regulated and Liver-Specific Tamarin Alpha Interferon Gene Delivery by a Helper-Dependent Adenoviral Vector

Gene therapy approaches based on liver-restricted and regulated alpha interferon (IFN-α) expression, recently shown to be effective in different murine hepatitis models, appear promising alternatives to inhibit hepatitis C virus (HCV) replication in patients and minimize side effects. Tamarins (Sagu...

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Autores principales: Aurisicchio, Luigi, De Tomassi, Amedeo, La Monica, Nicola, Ciliberto, Gennaro, Traboni, Cinzia, Palombo, Fabio
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Gene Delivery
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112151/
https://ncbi.nlm.nih.gov/pubmed/15890916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.11.6772-6780.2005
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