Deoxycytidyl-Deoxyguanosine Oligonucleotide Classes A, B, and C Induce Distinct Cytokine Gene Expression Patterns in Rhesus Monkey Peripheral Blood Mononuclear Cells and Distinct Alpha Interferon Responses in TLR9-Expressing Rhesus Monkey Plasmacytoid Dendritic Cells

To determine if deoxycytidyl-deoxyguanosine oligonucleotides (CpG ODN) can be used effectively as nonspecific inducers of innate immune defenses for preventative or therapeutic interventions in infectious disease models for nonhuman primates, the present study evaluated the response of rhesus monkey...

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Autores principales: Abel, Kristina, Wang, Yichuan, Fritts, Linda, Sanchez, Eleonora, Chung, Eugene, Fitzgerald-Bocarsly, Patricia, Krieg, Arthur M., Miller, Christopher J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Cellular Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112080/
https://ncbi.nlm.nih.gov/pubmed/15879022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.12.5.606-621.2005
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