Deletion of the Ferric Uptake Regulator Fur Impairs the In Vitro Growth and Virulence of Actinobacillus pleuropneumoniae

In order to investigate the role of the ferric uptake regulator Fur in the porcine lung pathogen Actinobacillus pleuropneumoniae, we constructed an isogenic in-frame deletion mutant, A. pleuropneumoniae Δfur. This mutant showed constitutive expression of transferrin-binding proteins, growth deficien...

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Autores principales: Jacobsen, Ilse, Gerstenberger, Jörg, Gruber, Achim D., Bossé, Janine T., Langford, Paul R., Hennig-Pauka, Isabel, Meens, Jochen, Gerlach, Gerald-F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111875/
https://ncbi.nlm.nih.gov/pubmed/15908404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3740-3744.2005
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