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Transcriptional Control of Impaired Th1 Responses in Patent Lymphatic Filariasis by T-Box Expressed in T Cells and Suppressor of Cytokine Signaling Genes

T-bet (T-box expressed in T cells) and GATA-3 are transcription factors that play a critical role in the development of Th1 and Th2 cells, as do genes of the SOCS (suppressor of cytokine signaling) family, albeit indirectly. Another transcription factor, Foxp3, is a master regulator of natural regul...

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Main Authors: Babu, Subash, Kumaraswami, V., Nutman, Thomas B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111868/
https://ncbi.nlm.nih.gov/pubmed/15908366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3394-3401.2005
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