Killing of dsrA Mutants of Haemophilus ducreyi by Normal Human Serum Occurs via the Classical Complement Pathway and Is Initiated by Immunoglobulin M Binding

Previously, we showed that serum resistance in Haemophilus ducreyi type strain 35000HP required expression of the outer membrane protein DsrA because the isogenic dsrA mutant FX517 is highly serum susceptible. In this study, we confirmed this finding by construction of additional serum-susceptible d...

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Detalhes bibliográficos
Main Authors: Abdullah, Malikah, Nepluev, Igor, Afonina, Galyna, Ram, Sanjay, Rice, Peter, Cade, William, Elkins, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111860/
https://ncbi.nlm.nih.gov/pubmed/15908371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3431-3439.2005
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