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Gamma Interferon Enhances Internalization and Early Nonoxidative Killing of Salmonella enterica Serovar Typhimurium by Human Macrophages and Modifies Cytokine Responses

Gamma interferon (IFN-γ) is a critical cytokine in host defense against salmonella infections, but its role in phagocytic killing of intracellular Salmonella spp. has been investigated mainly in animal rather than human cells. We measured the effect of recombinant IFN-γ (rIFN-γ) priming on bacterial...

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Détails bibliographiques
Auteurs principaux: Gordon, Melita A., Jack, Dominic L., Dockrell, David H., Lee, Margaret E., Read, Robert C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111838/
https://ncbi.nlm.nih.gov/pubmed/15908373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3445-3452.2005
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