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CD4(+) T Cells Play a Dominant Role in Protection against New World Leishmaniasis Induced by Vaccination with the P-4 Amastigote Antigen

Immunodepletion studies of P-4-vaccinated mice indicate that CD4(+) and not CD8(+) T cells are critical for protection against Leishmania pifanoi (Leishmania mexicana complex). Although a moderate CD8(+) T-cell response is elicited by vaccination, CD4(+) T cells are the dominant responding populatio...

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Bibliografske podrobnosti
Main Authors: Kar, Sujata, Metz, Christine, McMahon-Pratt, Diane
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111832/
https://ncbi.nlm.nih.gov/pubmed/15908422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3823-3827.2005
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