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Caenorhabditis elegans Inositol 5-Phosphatase Homolog Negatively Regulates Inositol 1,4,5-Triphosphate Signaling in Ovulation

Ovulation in Caenorhabditis elegans requires inositol 1,4,5-triphosphate (IP(3)) signaling activated by the epidermal growth factor (EGF)-receptor homolog LET-23. We generated a deletion mutant of a type I 5-phosphatase, ipp-5, and found a novel ovulation phenotype whereby the spermatheca hyperexten...

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Autors principals: Bui, Yen Kim, Sternberg, Paul W.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC111133/
https://ncbi.nlm.nih.gov/pubmed/12006659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-01-0008
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