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Paxillin-dependent Paxillin Kinase Linker and p21-Activated Kinase Localization to Focal Adhesions Involves a Multistep Activation Pathway

The precise temporal-spatial regulation of the p21-activated serine-threonine kinase PAK at the plasma membrane is required for proper cytoskeletal reorganization and cell motility. However, the mechanism by which PAK localizes to focal adhesions has not yet been elucidated. Indirect binding of PAK...

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Pubblicato in:Mol Biol Cell
Autori principali: Brown, Michael C., West, Kip A., Turner, Christopher E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12006652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.02-02-0015
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