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Paxillin-dependent Paxillin Kinase Linker and p21-Activated Kinase Localization to Focal Adhesions Involves a Multistep Activation Pathway
The precise temporal-spatial regulation of the p21-activated serine-threonine kinase PAK at the plasma membrane is required for proper cytoskeletal reorganization and cell motility. However, the mechanism by which PAK localizes to focal adhesions has not yet been elucidated. Indirect binding of PAK...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The American Society for Cell Biology
2002
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111126/ https://ncbi.nlm.nih.gov/pubmed/12006652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-02-0015 |
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