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Comparison between Human Cytomegalovirus pUL97 and Murine Cytomegalovirus (MCMV) pM97 Expressed by MCMV and Vaccinia Virus: pM97 Does Not Confer Ganciclovir Sensitivity

The UL97 protein (pUL97) of human cytomegalovirus (HCMV) is a protein kinase that also phosphorylates ganciclovir (GCV), but its biological function is not yet clear. The M97 protein (pM97) of mouse cytomegalovirus (MCMV) is the homolog of pUL97. First, we studied the consequences of genetic replace...

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Udgivet i:J Virol
Principais autores: Wagner, Markus, Michel, Detlef, Schaarschmidt, Peter, Vaida, Bianca, Jonjic, Stipan, Messerle, Martin, Mertens, Thomas, Koszinowski, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Recombination and Evolution
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044117/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10729-10736.2000
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