Genotypic, Phenotypic, and Modeling Studies of a Deletion in the β3-β4 Region of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Gene That Is Associated with Resistance to Nucleoside Reverse Transcriptase Inhibitors

Point mutations and inserts in the β3-β4 region of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) are associated with resistance to nucleoside analog inhibitors. This report describes HIV-1 strains from seven patients that were found to have a 3-bp deletion in the β3-β4 regio...

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Pubblicato in:	J Virol
Autori principali:	Winters, Mark A., Coolley, Kristi L., Cheng, Peng, Girard, Yvette A., Hamdan, Hasnah, Kovari, Ladislau C., Merigan, Thomas C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10707-10713.2000
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