Epstein-Barr Virus LMP2A Transforms Epithelial Cells, Inhibits Cell Differentiation, and Activates Akt

The Epstein-Barr virus LMP2A protein was expressed in a human keratinocyte cell line, HaCaT, and effects on epithelial cell growth were detected in organotypic raft cultures and in vivo in nude mice. Raft cultures derived from LMP2A-expressing cells were hyperproliferative, and epithelial differenti...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Scholle, Frank, Bendt, Katharine M., Raab-Traub, Nancy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10681-10689.2000
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